???? ?????? ?? ???? ???? ?????? ????? ???? ?? ???? ???? ???? ??? ??????? ??? ??? ???? ????? ??????? ???? ???? ??????.???? ?????? ?????? ?????? ????????? ??? ???? ?????? ??????. ???? ????? ??????? ???????? ???????:Utilization of opioids for an prolonged time period may possibly bring about reduced fertility in females and males of reproductive likel